Phenotypes associated with this allele

• Allele Symbol: Tcf21^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:7426017
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tcf21^em1(IMPC)Mbp/Tcf21^em1(IMPC)Mbp	C57BL/6NCrl-Tcf21^em1(IMPC)Mbp/MbpMmucd	MGI:7472276
ht2	Tcf21^em1(IMPC)Mbp/Tcf21^+	C57BL/6NCrl-Tcf21^em1(IMPC)Mbp/MbpMmucd	MGI:7472275

Genotype
MGI:7472276

hm1

• Allelic Composition: Tcf21^em1(IMPC)Mbp/Tcf21^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Tcf21^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tcf21

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♀

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:7472275

ht2

• Allelic Composition: Tcf21^em1(IMPC)Mbp/Tcf21⁺
• Genetic Background: C57BL/6NCrl-Tcf21^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tcf21

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

enlarged testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating calcium level ( J:211773 )

♂

IMPC - UCD

edema ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

enlarged testis ( J:211773 )

♂

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

♀

IMPC - UCD