Phenotypes associated with this allele

• Allele Symbol: Tmeff2^{em1(IMPC)Hmgu}
• Allele Name: endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:7426031
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmeff2^em1(IMPC)Hmgu/Tmeff2^em1(IMPC)Hmgu	C57BL/6NCrl-Tmeff2^em1(IMPC)Hmgu/Ieg	MGI:7629121
ht2	Tmeff2^em1(IMPC)Hmgu/Tmeff2^+	C57BL/6NCrl-Tmeff2^em1(IMPC)Hmgu/Ieg	MGI:7629120

Genotype
MGI:7629121

hm1

• Allelic Composition: Tmeff2^{em1(IMPC)Hmgu}/Tmeff2^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6NCrl-Tmeff2^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Tmeff2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:7629120

ht2

• Allelic Composition: Tmeff2^{em1(IMPC)Hmgu}/Tmeff2⁺
• Genetic Background: C57BL/6NCrl-Tmeff2^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Tmeff2

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

♂

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal optic disk morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

♂

IMPC - HMGU