Phenotypes associated with this allele

• Allele Symbol: Tnfrsf1a^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7426125
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tnfrsf1a^em1(IMPC)Ccpcz/Tnfrsf1a^em1(IMPC)Ccpcz	C57BL/6NCrl-Tnfrsf1a^em1(IMPC)Ccpcz/Ccpcz	MGI:7472291

Genotype
MGI:7472291

hm1

• Allelic Composition: Tnfrsf1a^{em1(IMPC)Ccpcz}/Tnfrsf1a^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Tnfrsf1a^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Tnfrsf1a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

increased neutrophil cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased NK cell number ( J:211773 )

IMPC - CCP-IMG

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased NK cell number ( J:211773 )

IMPC - CCP-IMG

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - CCP-IMG