mortality/aging
IMPC - JAX
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• although blastocysts are recovered at expected Mendelian ratios at E3.5, no homozygous embryos can be recovered at E7.5
• however, excess resorption sites suggest that embryos elicit a decidual response in vivo
• in vitro, blastocysts hatch from the zona pellucida and form typical outgrowth colonies after 3 days in culture
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