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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr124128tm1.1Jfer
targeted mutation 1.1, Jorge Ferrer
MGI:7431269
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rr124128tm1.1Jfer/Rr124128tm1.1Jfer
Tg(Pdx1-cre)6Tuv/0 		involves: C57BL/6 * FVB/N MGI:7431290


Genotype
MGI:7431290
cn1
Allelic
Composition		 Rr124128tm1.1Jfer/Rr124128tm1.1Jfer
Tg(Pdx1-cre)6Tuv/0
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr124128tm1.1Jfer mutation (0 available); any Rr124128 mutation (0 available)
Tg(Pdx1-cre)6Tuv mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
growth/size/body region phenotype ( J:332319 )
N
• normal growth and morphology

homeostasis/metabolism
hyperglycemia ( J:332319 )
• fasting hyperglycaemia by age 8 weeks
decreased circulating insulin level ( J:332319 )
• insulin deficiency by age 8 weeks
impaired glucose tolerance ( J:332319 )
• glucose intolerance by age 8 weeks

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
diabetes mellitus DOID:9351 J:332319




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory