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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rimklatm1.1Meck
targeted mutation 1.1, Matthias Eckhardt
MGI:7432669
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rimklatm1.1Meck/Rimklatm1.1Meck involves: 129P2/OlaHsd * C57BL/6NCrl MGI:7432674


Genotype
MGI:7432674
hm1
Allelic
Composition
Rimklatm1.1Meck/Rimklatm1.1Meck
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rimklatm1.1Meck mutation (0 available); any Rimkla mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice are impaired in a short-term delay novel object recognition test, unable to discriminate between a novel and familiar object
• mice show reduced activity in the open field test, showing reduced distance traveled
• however, mice show no obvious behavioral abnormalities in the home cage, no differences in rearing activity or in the dark-light transition test (anxiety), and no impairment in motor coordination on the accelerating rotarod test

vision/eye
N
• mice show no evidence of visual impairment in testing optokinetic behavior using an optokinetic drum





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory