behavior/neurological
• mice are impaired in a short-term delay novel object recognition test, unable to discriminate between a novel and familiar object
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• mice show reduced activity in the open field test, showing reduced distance traveled
• however, mice show no obvious behavioral abnormalities in the home cage, no differences in rearing activity or in the dark-light transition test (anxiety), and no impairment in motor coordination on the accelerating rotarod test
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vision/eye
N |
• mice show no evidence of visual impairment in testing optokinetic behavior using an optokinetic drum
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