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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdh2em2Obir
endonuclease-mediated mutation 2, Ohad S Birk
MGI:7432736
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdh2em2Obir/Cdh2em2Obir C57BL/6JRcc-Cdh2em2Obir MGI:7434354


Genotype
MGI:7434354
hm1
Allelic
Composition		 Cdh2em2Obir/Cdh2em2Obir
Genetic
Background		 C57BL/6JRcc-Cdh2em2Obir
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh2em2Obir mutation (0 available); any Cdh2 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperactivity ( J:331911 )
• 12-week-old males mice exhibit a greater traveling distance, increased velocity, prolonged mobility time, and an increase in the number of center zone alternation in the open field test
• acute methylphenidate intervention aggravates locomotor activity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory