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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(15Rr357-Rr303293)2Jta
deletion, Chr 15, Jussi Taipale 2
MGI:7434631
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta involves: C57BL/6 MGI:7434698
cx2
 		ApcMin/Apc+
Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta 		involves: C57BL/6 MGI:7434699


Genotype
MGI:7434698
hm1
Allelic
Composition		 Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of tumors by chemical induction ( J:257088 )
• increased median tumor-free survival time (from 88 days in WT to >120 days) after mammary tumor-inducing DMBA/MPA treatment
• normal susceptibility to BBN-induced bladder tumors

endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:257088 )
N
• normal mammary gland histology

growth/size/body
growth/size/body region phenotype ( J:257088 )
N
• no obvious phenotype

homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:257088 )
• increased median tumor-free survival time (from 88 days in WT to >120 days) after mammary tumor-inducing DMBA/MPA treatment
• normal susceptibility to BBN-induced bladder tumors

immune system
immune system phenotype ( J:257088 )
N
• normal spleen histology

mortality/aging
mortality/aging ( J:257088 )
N
• viable

digestive/alimentary system
digestive/alimentary phenotype ( J:257088 )
N
• normal colon histology

renal/urinary system
renal/urinary system phenotype ( J:257088 )
N
• normal bladder histology

reproductive system
reproductive system phenotype ( J:257088 )
N
• normal prostate histology
• fertile




Genotype
MGI:7434699
cx2
Allelic
Composition		 ApcMin/Apc+
Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (158 available)
Del(15Rr357-Rr303293)2Jta mutation (0 available); any Del(15Rr357-Rr303293)2Jta mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system

neoplasm




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory