Phenotypes associated with this allele

• Allele Symbol: Klk10^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7438344
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Klk10^em1(IMPC)Ccpcz/Klk10^em1(IMPC)Ccpcz	C57BL/6NCrl-Klk10^em1(IMPC)Ccpcz/Ccpcz	MGI:7629030

Genotype
MGI:7629030

hm1

• Allelic Composition: Klk10^{em1(IMPC)Ccpcz}/Klk10^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Klk10^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Klk10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - CCP-IMG

cardiovascular system

cardiovascular system phenotype ( J:211773 )

♀

IMPC - CCP-IMG

abnormal sinus arrhythmia ( J:211773 )

♀

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased CD8-positive, naive alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased effector memory T-helper cell number ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating chloride level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased CD8-positive, naive alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased effector memory T-helper cell number ( J:211773 )

IMPC - CCP-IMG