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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr381em2Kap
endonuclease-mediated mutation 2, Dietmar J Kappes
MGI:7439127
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr381em2Kap/Rr381em2Kap involves: C57BL/6 MGI:7439197
cx2
 		B2mtm1Unc/B2mtm1Unc
Rr381em2Kap/Rr381em2Kap 		involves: 129P2/OlaHsd * C57BL/6 MGI:7439201
cx3
 		H2dlAb1-Ea/H2dlAb1-Ea
Rr381em2Kap/Rr381em2Kap 		involves: 129S2/SvPas * C57BL/6 MGI:7439200
cx4
 		Rr381em2Kap/Rr381em2Kap
Tg(TcraTcrb)1100Mjb/0 		involves: C57BL/6 MGI:7439198
cx5
 		Rr381em2Kap/Rr381em2Kap
Tg(TcrAND)53Hed/0 		involves: C57BL/6 * SJL MGI:7439199


Genotype
MGI:7439197
hm1
Allelic
Composition		 Rr381em2Kap/Rr381em2Kap
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:333471 )
N
• normal single-positive (SP) CD4+ to CD8+ T cell ratio
• normal proportions of SP CD8+ thymocytes and mature CD8+ T cells




Genotype
MGI:7439201
cx2
Allelic
Composition		 B2mtm1Unc/B2mtm1Unc
Rr381em2Kap/Rr381em2Kap
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Unc mutation (38 available); any B2m mutation (122 available)
Rr381em2Kap mutation (0 available); any Rr381 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

immune system




Genotype
MGI:7439200
cx3
Allelic
Composition		 H2dlAb1-Ea/H2dlAb1-Ea
Rr381em2Kap/Rr381em2Kap
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2dlAb1-Ea mutation (13 available); any H2 mutation (282 available)
Rr381em2Kap mutation (0 available); any Rr381 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

immune system




Genotype
MGI:7439198
cx4
Allelic
Composition		 Rr381em2Kap/Rr381em2Kap
Tg(TcraTcrb)1100Mjb/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr381em2Kap mutation (0 available); any Rr381 mutation (0 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:333471 )
N
• normal MHC class-specific T cell development




Genotype
MGI:7439199
cx5
Allelic
Composition		 Rr381em2Kap/Rr381em2Kap
Tg(TcrAND)53Hed/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr381em2Kap mutation (0 available); any Rr381 mutation (0 available)
Tg(TcrAND)53Hed mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:333471 )
N
• normal MHC class-specific T cell development




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory