All Phenotypes Fer1l5<tm1Osb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fer1l5^tm1Osb
targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:7439947

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fer1l5^tm1Osb/Fer1l5^tm1Osb	STOCK Fer1l5^tm1Osb/75Osb	MGI:7441950

Allelic Composition	Fer1l5^tm1Osb/Fer1l5^tm1Osb
Genetic Background	STOCK Fer1l5^tm1Osb/75Osb

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fer1l5^tm1Osb mutation (2 available); any Fer1l5 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:333204 )

N	• female mice are fertile

reduced male fertility ( J:333204 )

• male fertility is severely impaired

• however, transgenic expression of a FLAG or PA-tagged versions rescues fertility

impaired acrosome reaction ( J:333204 )

• spermatozoa cannot undergo the acrosome reaction in vitro or in vivo

• however, transgenic expression of a FLAG or PA-tagged versions rescues acrosome reaction

failure of sperm-egg fusion ( J:333204 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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