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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr388em1Jdai
endonuclease-mediated mutation 1, Jianwu Dai
MGI:7440074
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr388em1Jdai/Rr388em1Jdai Not Specified MGI:7447204
cx2
 		Rr388em1Jdai/Rr388em1Jdai
Rr397em1Zyliu/Rr397em1Zyliu 		Not Specified MGI:7447207


Genotype
MGI:7447204
hm1
Allelic
Composition		 Rr388em1Jdai/Rr388em1Jdai
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
decreased cochlear inner hair cell number ( J:333396 )
• reduced density in basal turn at age P1 and P30
decreased cochlear outer hair cell number ( J:333396 )
• third row is missing or discontinuous on lateral side in basal turn at age P1 and P30
increased or absent threshold for auditory brainstem response ( J:333396 )
• at 32 kHz
• normal at lower frequencies

embryo
embryo phenotype ( J:333396 )
• viable

mortality/aging
mortality/aging ( J:333396 )
• viable and normal lifespan

nervous system
nervous system phenotype ( J:333396 )
• normal cerebellum morphology at age P30
decreased cochlear inner hair cell number ( J:333396 )
• reduced density in basal turn at age P1 and P30
decreased cochlear outer hair cell number ( J:333396 )
• third row is missing or discontinuous on lateral side in basal turn at age P1 and P30




Genotype
MGI:7447207
cx2
Allelic
Composition		 Rr388em1Jdai/Rr388em1Jdai
Rr397em1Zyliu/Rr397em1Zyliu
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:333396 )
N
• normal cochlear length at age P1
decreased cochlear inner hair cell number ( J:333396 )
• reduced density in all turns at age P1
decreased cochlear outer hair cell number ( J:333396 )
• reduced density in all turns at age P1

embryo
embryo phenotype ( J:333396 )
• viable

mortality/aging
mortality/aging ( J:333396 )
• viable and normal lifespan

nervous system
nervous system phenotype ( J:333396 )
• normal cerebellum morphology at age P30
decreased cochlear inner hair cell number ( J:333396 )
• reduced density in all turns at age P1
decreased cochlear outer hair cell number ( J:333396 )
• reduced density in all turns at age P1




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory