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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Qpctltm1.1Gne
targeted mutation 1.1, Genentech
MGI:7442900
Summary 2 genotypes


Genotype
MGI:7442910
hm1
Allelic
Composition		 Qpctltm1.1Gne/Qpctltm1.1Gne
Genetic
Background		 C57BL/6N-Qpctltm1.1Gne
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Qpctltm1.1Gne mutation (0 available); any Qpctl mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased monocyte cell number ( J:324112 )
• in the blood and spleen
increased monocyte cell number ( J:324112 )
• in the bone marrow

neoplasm
decreased tumor growth/size ( J:324112 )
• mice exhibit attenuated tumor growth compared with wild-type mice

hematopoietic system
decreased monocyte cell number ( J:324112 )
• in the blood and spleen
increased monocyte cell number ( J:324112 )
• in the bone marrow




Genotype
MGI:7442916
cx2
Allelic
Composition		 Qpcttm1.1Gne/Qpcttm1.1Gne
Qpctltm1.1Gne/Qpctltm1.1Gne
Genetic
Background		 C57BL/6N-Qpctltm1.1Gne Qpcttm1.1Gne
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Qpctltm1.1Gne mutation (0 available); any Qpctl mutation (14 available)
Qpcttm1.1Gne mutation (0 available); any Qpct mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased monocyte cell number ( J:324112 )
• in the blood, spleen, and bone marrow

immune system
decreased monocyte cell number ( J:324112 )
• in the blood, spleen, and bone marrow




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory