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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lgi2tm1.2Mejr
targeted mutation 1.2, Dies Meijer
MGI:7444283
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lgi2tm1.2Mejr/Lgi2tm1.2Mejr Not Specified MGI:7444414
cx2
 		Lgi2tm1.2Mejr/Lgi2tm1.2Mejr
Lgi3tm1.2Mejr/Lgi3tm1.2Mejr 		Not Specified MGI:7444417


Genotype
MGI:7444414
hm1
Allelic
Composition		 Lgi2tm1.2Mejr/Lgi2tm1.2Mejr
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lgi2tm1.2Mejr mutation (0 available); any Lgi2 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:333962 )
• mice develop normally with normal lifespans and fertility




Genotype
MGI:7444417
cx2
Allelic
Composition		 Lgi2tm1.2Mejr/Lgi2tm1.2Mejr
Lgi3tm1.2Mejr/Lgi3tm1.2Mejr
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lgi2tm1.2Mejr mutation (0 available); any Lgi2 mutation (28 available)
Lgi3tm1.2Mejr mutation (0 available); any Lgi3 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
abnormal neuron morphology ( J:333962 )
• absent Kv1 channels complex accumulation at the juxtaparanodal membrane in neurons

growth/size/body
postnatal growth retardation ( J:333962 )

behavior/neurological
tremors ( J:333962 )
• from the second postnatal week




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory