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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hacd2tm1c(EUCOMM)Hmgu
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:7444803
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Hacd2tm1b(EUCOMM)Hmgu/Hacd2tm1c(EUCOMM)Hmgu
Tg(Tek-cre)1Ywa/0 		involves: C57BL/6 * C57BL/6N * SJL MGI:7447126
cn2
 		Hacd2tm1b(EUCOMM)Hmgu/Hacd2tm1c(EUCOMM)Hmgu
Mesp1tm2(cre)Ysa/Mesp1+ 		involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj MGI:7447132


Genotype
MGI:7447126
cn1
Allelic
Composition		 Hacd2tm1b(EUCOMM)Hmgu/Hacd2tm1c(EUCOMM)Hmgu
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: C57BL/6 * C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hacd2tm1b(EUCOMM)Hmgu mutation (0 available); any Hacd2 mutation (18 available)
Hacd2tm1c(EUCOMM)Hmgu mutation (0 available); any Hacd2 mutation (18 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:333944 )
• all mice are viable and overtly normal and reach adulthood in healthy conditions; moreover, E10.5 embryos show normal yolk sac vascularization and cardiovascular development




Genotype
MGI:7447132
cn2
Allelic
Composition		 Hacd2tm1b(EUCOMM)Hmgu/Hacd2tm1c(EUCOMM)Hmgu
Mesp1tm2(cre)Ysa/Mesp1+
Genetic
Background		 involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hacd2tm1b(EUCOMM)Hmgu mutation (0 available); any Hacd2 mutation (18 available)
Hacd2tm1c(EUCOMM)Hmgu mutation (0 available); any Hacd2 mutation (18 available)
Mesp1tm2(cre)Ysa mutation (3 available); any Mesp1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:333944 )
• all mice are viable and overtly normal and reach adulthood in healthy conditions; moreover, adult mice exhibit normal echocardiographic parameters




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory