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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rr253em5Kmm
endonuclease-mediated mutation 5, Kenneth M Murphy
MGI:7448466
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rr253em5Kmm/Rr253em5Kmm C57BL/6J-Rr253em5Kmm MGI:7448522


Genotype
MGI:7448522
hm1
Allelic
Composition
Rr253em5Kmm/Rr253em5Kmm
Genetic
Background
C57BL/6J-Rr253em5Kmm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr253em5Kmm mutation (0 available); any Rr253 mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• reduction of cDC2 numbers
• increase of cDC1 numbers

immune system
• reduction of cDC2 numbers
• increase of cDC1 numbers





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory