Phenotypes associated with this allele

• Allele Symbol: Rr364729^em1Almk
• Allele Name: endonuclease-mediated mutation 1, Alasdair MacKenzie
• Allele ID: MGI:7448757
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr364729^em1Almk/Rr364729^em1Almk	C57BL/6-Rr364729^em1Almk	MGI:7448875

Genotype
MGI:7448875

hm1

• Allelic Composition: Rr364729^em1Almk/Rr364729^em1Almk
• Genetic Background: C57BL/6-Rr364729^em1Almk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:334318 , J:334339 )

N • normal food intake on standard chow (J:334318)

N • normal bitter vs sweet vs plain water preferences (J:334339)

N • normal behavior in open field test (OFT) and elevated zero maze (EZM) in females (J:334339)

low alcohol preference ( J:334339 )

abnormal food preference ( J:334318 )

• reduced preference for high-fat diet (HFD) given choice between HFD and LFD

• normal total food intake

decreased anxiety-related response ( J:334339 )

♂ • decreased latency in time taken by fasted animals to first bite of food in novel environment in novelty suppressed feeding test (NSFT)

♂ • increase in entries into center, time spent in center and total distance traveled in open field test (OFT)

♂ • increased time spent in open quadrants, total distance traveled and crossings between light and dark sides in elevated zero maze (EZM)

♂ • reduced frequency and latency of freezing behavior in elevated zero maze (EZM)

♂ • normal behavior in open field test (OFT) and elevated zero maze (EZM) in females

♂ • increased marble burying in marble burying test (MBT) in males and females

♂ • increased distance traveled and number of crossings between peripheral and central zones in novelty suppressed feeding test (NSFT) in males and females

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:334318 )

N • normal metabolism on standard chow

embryo

embryo phenotype ( J:334339 )

N • viable and healthy

growth/size/body

growth/size/body region phenotype ( J:334318 )

N • normal weight gain on standard chow