Phenotypes associated with this allele

• Allele Symbol: Nubpl^em1Vkim
• Allele Name: endonuclease-mediated mutation 1, Virginia Kimonis
• Allele ID: MGI:7449244
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nubpl^em1Vkim/Nubpl^em1Vkim	C57BL/6NJ-Nubpl^em1Vkim	MGI:7449276
ht2	Nubpl^em1Vkim/Nubpl^tm1a(KOMP)Wtsi	C57BL/6N-Nubpl^em1Vkim Nubpl^tm1a(KOMP)Wtsi	MGI:7449280

Genotype
MGI:7449276

hm1

• Allelic Composition: Nubpl^em1Vkim/Nubpl^em1Vkim
• Genetic Background: C57BL/6NJ-Nubpl^em1Vkim

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:333699 )

• no embryos found at stage E10.5

Genotype
MGI:7449280

ht2

• Allelic Composition: Nubpl^em1Vkim/Nubpl^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Nubpl^em1Vkim Nubpl^{tm1a(KOMP)Wtsi}

behavior/neurological

behavior/neurological phenotype ( J:333699 )

N • normal feet clasping

N • no behavior phenotype

cellular

cellular phenotype ( J:333699 )

N • no signs of oxidative stress

embryo

embryo phenotype ( J:333699 )

N • mice born at normal Mendelian ratios

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:333699 )

N • no hearing phenotype

mortality/aging

mortality/aging ( J:333699 )

N • no aging phenotype

nervous system

nervous system phenotype ( J:333699 )

N • no nervous system phenotype

vision/eye

vision/eye phenotype ( J:333699 )

N • no vision phenotype