mortality/aging
• homozygous embryos can be recovered at E3.5 and appear as compacting morulae; no homozygous embryos or excess resorption sites are observed at E7.5
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IMPC - JAX
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embryo
• in vivo, embryos exhibit a compacting morula morphology at E3.5
• in vitro, embryos do not hatch and are dead after 3 days in culture
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• in vitro outgrowth assays show that embryos fail to hatch from the zona pellucida after 3 days in culture
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• embryos recovered at E3.5 appear as compacting morulae
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growth/size/body
• embryos recovered at E3.5 appear as compacting morulae
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