Phenotypes associated with this allele

• Allele Symbol: Adad2^em2Shnk
• Allele Name: endonuclease-mediated mutation 2, Satoshi H Namekawa
• Allele ID: MGI:7450908
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adad2^em2Shnk/Adad2^em2Shnk	C57BL/6-Adad2^em2Shnk	MGI:7450944

Genotype
MGI:7450944

hm1

• Allelic Composition: Adad2^em2Shnk/Adad2^em2Shnk
• Genetic Background: C57BL/6-Adad2^em2Shnk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

azoospermia ( J:334463 )

♂ • absence of spermatozoa

abnormal acrosome morphology ( J:334463 )

♂ • occasionally bi-nuclear with proacrosomic vesicles that fail to flatten

abnormal male meiosis ( J:334463 )

♂ • defective P-body integrity

decreased testis weight ( J:334463 )

♂ • mild

arrest of spermiogenesis ( J:334463 )

♂

male infertility ( J:334463 )

♂

endocrine/exocrine glands

decreased testis weight ( J:334463 )

♂ • mild

cellular

azoospermia ( J:334463 )

♂ • absence of spermatozoa

abnormal acrosome morphology ( J:334463 )

♂ • occasionally bi-nuclear with proacrosomic vesicles that fail to flatten

abnormal male meiosis ( J:334463 )

♂ • defective P-body integrity