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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adad2em2Shnk
endonuclease-mediated mutation 2, Satoshi H Namekawa
MGI:7450908
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adad2em2Shnk/Adad2em2Shnk C57BL/6-Adad2em2Shnk MGI:7450944


Genotype
MGI:7450944
hm1
Allelic
Composition		 Adad2em2Shnk/Adad2em2Shnk
Genetic
Background		 C57BL/6-Adad2em2Shnk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adad2em2Shnk mutation (0 available); any Adad2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
azoospermia ( J:334463 )
• absence of spermatozoa
abnormal acrosome morphology ( J:334463 )
• occasionally bi-nuclear with proacrosomic vesicles that fail to flatten
abnormal male meiosis ( J:334463 )
• defective P-body integrity

endocrine/exocrine glands

cellular
azoospermia ( J:334463 )
• absence of spermatozoa
abnormal acrosome morphology ( J:334463 )
• occasionally bi-nuclear with proacrosomic vesicles that fail to flatten
abnormal male meiosis ( J:334463 )
• defective P-body integrity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory