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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ctnnb1em1V
endonuclease-mediated mutation 1, ViewSolid Biotech Co., Ltd
MGI:7466919
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Ctnnb1em1V/Ctnnb1em1V
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
involves: C57BL/6 * C57BL/6J * CBA MGI:7467133


Genotype
MGI:7467133
cn1
Allelic
Composition
Ctnnb1em1V/Ctnnb1em1V
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
Genetic
Background
involves: C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1em1V mutation (0 available); any Ctnnb1 mutation (49 available)
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• delayed superficial blood vessel growth and defects in vertical blood vessel growth in retina at age P9 after tamoxifen administration from age P1-P4
• absent secondary and tertiary blood vessels in deeper layers of retina at age P9 after tamoxifen administration from age P1-P4
• mild delay of blood vessel growth in deeper layers of retina at age P13 after tamoxifen administration from age P6

vision/eye
• delayed superficial blood vessel growth and defects in vertical blood vessel growth at age P9 after tamoxifen administration from age P1-P4
• absent secondary and tertiary blood vessels in deeper layers at age P9 after tamoxifen administration from age P1-P4
• mild delay of blood vessel growth in deeper layers at age P13 after tamoxifen administration from age P6

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
exudative vitreoretinopathy DOID:0050535 OMIM:PS133780
J:328283





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory