Phenotypes associated with this allele

• Allele Symbol: Lrp5^em1Xjz
• Allele Name: endonuclease-mediated mutation 1, Xianjun Zhu
• Allele ID: MGI:7466960
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrp5^em1Xjz/Lrp5^em1Xjz	C57BL/6J-Lrp5^em1Xjz	MGI:7467137

Genotype
MGI:7467137

hm1

• Allelic Composition: Lrp5^em1Xjz/Lrp5^em1Xjz
• Genetic Background: C57BL/6J-Lrp5^em1Xjz

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased angiogenesis ( J:328283 )

• delayed superior blood vessel growth and defects in vertical blood vessel growth in retina at age P6

• absent secondary and tertiary blood vessels in deeper layers of retina at age P6

• delayed blood vessel growth in deeper layers of retina at age P13

vision/eye

abnormal retina development ( J:328283 )

• delayed superior blood vessel growth and defects in vertical blood vessel growth at age P6

• absent secondary and tertiary blood vessels in deeper layers at age P6

• delayed blood vessel growth in deeper layers at age P13

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
exudative vitreoretinopathy		DOID:0050535	OMIM:PS133780	J:328283