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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ctnnb1tm1.1Smoc
targeted mutation 1.1, Shanghai Model Organisms Center
MGI:7490339
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ctnnb1tm1.1Smoc/Ctnnb1tm1.1Smoc
Sox9em1(cre/ERT2)Tchn/Sox9+ 		involves: C57BL/6 MGI:7491703


Genotype
MGI:7491703
cn1
Allelic
Composition		 Ctnnb1tm1.1Smoc/Ctnnb1tm1.1Smoc
Sox9em1(cre/ERT2)Tchn/Sox9+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1.1Smoc mutation (0 available); any Ctnnb1 mutation (49 available)
Sox9em1(cre/ERT2)Tchn mutation (1 available); any Sox9 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased incidence of tumors by chemical induction ( J:322311 )
• increased number of azoxymethane/dextran sodium sulfate (AOM/DSS)-induced colorectal adenocarcinomas and more aggressive progression of colorectal carcinogenesis

neoplasm
increased incidence of tumors by chemical induction ( J:322311 )
• increased number of azoxymethane/dextran sodium sulfate (AOM/DSS)-induced colorectal adenocarcinomas and more aggressive progression of colorectal carcinogenesis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory