Analysis Tools
reproductive system
 N |
• normal testis weight, morphology and sperm production at age 12 weeks
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• 33% of oocytes after hormone-induced ovulation were abnormal at age 6 weeks
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• at age 12 weeks
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• 2x normal mass owing to 4x increase in number of corpora lutea at ages 12 and 24 weeks
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• at age 24 weeks
• normal uterus weight at age 12 weeks
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• 4x normal number of oocytes per natural cycle at age 6 to 8 weeks
• normal number of atretic antral follicles at ages 12 and 24 weeks
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• 1.5x normal number of oocytes per hormone-induced cycle at age 6 to 8 weeks
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• 28% pups stillborn, 34% dead by age P5, 13% dead by age P11
• 3.3x more resorption sites at 17.5 dpc
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endocrine/exocrine glands
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N |
• normal number of primordial follicles at ages 12 and 24 weeks
• no ovarian tumors at age 12 weeks
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• at age 12 weeks
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• 2x normal mass owing to 4x increase in number of corpora lutea at ages 12 and 24 weeks
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growth/size/body
| N |
• no cachexia at age 12 weeks in females
• normal body weight and fat and lean mass at age 12 weeks in males
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• 2x normal mass owing to 4x increase in number of corpora lutea at ages 12 and 24 weeks
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homeostasis/metabolism
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N |
• normal serum progesterone levels at metestrus at age 12 weeks and in pregnant females
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cellular
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• 33% of oocytes after hormone-induced ovulation were abnormal at age 6 weeks
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• 3.3x more resorption sites at 17.5 dpc
• 28% pups stillborn, 34% dead by age P5, 13% dead by age P11
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