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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhoqtm1c(EUCOMM)Hmgu
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:7492304
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rhoqtm1c(EUCOMM)Hmgu/Rhoqtm1c(EUCOMM)Hmgu
Tg(Atf3-GFP*,-cre)#Hiki/0 		involves: C57BL/6 * C57BL/6N * DBA/2 MGI:7525602


Genotype
MGI:7525602
cn1
Allelic
Composition		 Rhoqtm1c(EUCOMM)Hmgu/Rhoqtm1c(EUCOMM)Hmgu
Tg(Atf3-GFP*,-cre)#Hiki/0
Genetic
Background		 involves: C57BL/6 * C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhoqtm1c(EUCOMM)Hmgu mutation (0 available); any Rhoq mutation (16 available)
Tg(Atf3-GFP*,-cre)#Hiki mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal peripheral nervous system regeneration ( J:308705 )
• mice show defective motor axon regeneration in injured hypoglossal nerves; at 4 weeks after axotomy, only ~10% of motor neurons are Fluoro-Gold (FG)-positive (regenerated) in injured hypoglossal nuclei versus ~60% FG-positive (regenerated) cells in control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory