All Phenotypes Iars1<em2Nsas> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Iars1^em2Nsas
endonuclease-mediated mutation 2, Nobuya Sasaki
MGI:7493276

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Iars1^em2Nsas/Iars1^em2Nsas	C57BL/6-Iars1^em2Nsas	MGI:7543396

Allelic Composition	Iars1^em2Nsas/Iars1^em2Nsas
Genetic Background	C57BL/6-Iars1^em2Nsas

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Iars1^em2Nsas mutation (0 available); any Iars1 mutation (78 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:340986 )

• at ages 2, 4, 8 and 14 weeks

homeostasis/metabolism

• at age 2 weeks

abnormal metabolism ( J:340986 )

• increased serum ornithine carbamoyltransferase (OCT) levels at age 2 weeks

liver/biliary system

liver/biliary system phenotype ( J:340986 )

N	• no liver failure at age 16 weeks

• at age 2 weeks

microvesicular hepatic steatosis ( J:340986 )

• at age 2 weeks

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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