About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpatch2em1Boui
endonuclease-mediated mutation 1, Philippe Bouillet
MGI:7514926
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gpatch2em1Boui/Gpatch2em1Boui C57BL/6-Gpatch2em1Boui MGI:7514934


Genotype
MGI:7514934
hm1
Allelic
Composition		 Gpatch2em1Boui/Gpatch2em1Boui
Genetic
Background		 C57BL/6-Gpatch2em1Boui
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpatch2em1Boui mutation (0 available); any Gpatch2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:336774 )
N
• no significant difference in response to LPS, LPS-induced TNF production by macrophages, or response in the SMAC-mimetic induced skin inflammation assay
decreased B cell number ( J:336774 )
• small but significant reduction in the frequency of B cells in the blood

reproductive system
reproductive system phenotype ( J:336774 )
N
• males and females are fertile

hematopoietic system
decreased B cell number ( J:336774 )
• small but significant reduction in the frequency of B cells in the blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory