All Phenotypes Svep1<em1Nost> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Svep1^em1Nost
endonuclease-mediated mutation 1, Nathan O Stitziel
MGI:7516157

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Apoe^tm1Unc/Apoe^tm1Unc Svep1^em1Nost/Svep1^em1Nost	involves: 129P2/OlaHsd * C57BL/6	MGI:7516347

Allelic Composition	Apoe^tm1Unc/Apoe^tm1Unc Svep1^em1Nost/Svep1^em1Nost
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoe^tm1Unc mutation (33 available); any Apoe mutation (158 available)
Svep1^em1Nost mutation (0 available); any Svep1 mutation (169 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:304349 )

N	• normal development of atherosclerotic plaque after 8 and 16 weeks of HFD feeding

growth/size/body

growth/size/body region phenotype ( J:304349 )

N	• normal body weight after 8 and 16 weeks of HFD feeding

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:304349 )

N	• normal serum total cholesterol, triglycerides and glucose levels after 8 and 16 weeks of HFD feeding

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	coronary artery disease	DOID:3393	OMIM:300464 OMIM:607339 OMIM:608316 OMIM:608318 OMIM:608320 OMIM:610947 OMIM:611139 OMIM:612030 OMIM:614293	J:304349

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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