All Phenotypes Ube3a<em1Mjz> MGI Mouse

Phenotypes associated with this allele

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ube3a^em1Mjz/Ube3a^em1Mjz	C57BL/6J-Ube3a^em1Mjz	MGI:7520325
ht2	Ube3a^em1Mjz/Ube3a⁺	C57BL/6J-Ube3a^em1Mjz	MGI:7520328

Allelic Composition	Ube3a^em1Mjz/Ube3a^em1Mjz
Genetic Background	C57BL/6J-Ube3a^em1Mjz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube3a^em1Mjz mutation (0 available); any Ube3a mutation (68 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:338299 )

N	• normal preference for unfamiliar mouse in three-chamber test if maternal or both maternal and paternal allele inherited

abnormal motor learning ( J:338299 )

• longer latency to fall in accelerating rotarod test if both maternal and paternal allele inherited

decreased thigmotaxis ( J:338299 )

• more time spent in center in open field test at age 50 weeks if both maternal and paternal allele inherited

• normal time spent in center in open field test at age up to 44 weeks if both maternal and paternal allele inherited

increased vertical activity ( J:338299 )

• increased time rearing in open field test at ages 30 and 50 weeks if both maternal and paternal allele inherited

increased locomotor activity ( J:338299 )

• increased distance traveled in open field test if both maternal and paternal allele inherited

• increased entry times in three-chamber test if both maternal and paternal allele inherited

embryo

embryo phenotype ( J:338299 )

N	• mice born at normal Mendelian ratios

growth/size/body

growth/size/body region phenotype ( J:338299 )

N	• normal body weight

nervous system

nervous system phenotype ( J:338299 )

N	• normal brain weight and cortical thickness, organization and excitatory neuron numbers

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:338299 )

N	• normal time rearing in open field test if maternal or paternal allele inherited

abnormal motor learning ( J:338299 )

• longer latency to fall in accelerating rotarod test if maternal allele inherited

• normal latency to fall in accelerating rotarod test if paternal allele inherited

decreased thigmotaxis ( J:338299 )

• more time spent in center in open field test at age 50 weeks if maternal allele inherited

• normal time spent in center in open field test at age up to 44 weeks if maternal allele inherited

• normal behavior in open field test if paternal allele inherited

increased locomotor activity ( J:338299 )

• increased distance traveled in open field test if maternal allele inherited

• increased entry times in three-chamber test if maternal allele inherited

• normal behavior in open field test if paternal allele inherited

• normal entry times in three-chamber test if paternal allele inherited

decreased social investigation ( J:338299 )

• no preference for unfamiliar mouse in three-chamber test if paternal allele inherited

• normal preference for unfamiliar mouse in three-chamber test if maternal allele inherited