About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc25a32em1Liliu
endonuclease-mediated mutation 1, Li Liu
MGI:7520348
Summary 2 genotypes


Genotype
MGI:7520401
hm1
Allelic
Composition
Slc25a32em1Liliu/Slc25a32em1Liliu
Genetic
Background
C57BL/6-Slc25a32em1Liliu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a32em1Liliu mutation (0 available); any Slc25a32 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal gait (no clubfoot)
• normal motor function in hanging wire, rotarod and forced swimming tests

embryo
N
• mice born at normal Mendelian ratios

growth/size/body
N
• normal body weight and neonatal growth rate

homeostasis/metabolism
N
• normal folate intermediate levels in mitochondria
• normal carnitine levels




Genotype
MGI:7520405
ht2
Allelic
Composition
Slc25a32em1Liliu/Slc25a32em2Liliu
Genetic
Background
C57BL/6-Slc25a32em1Liliu/Slc25a32em2Liliu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a32em1Liliu mutation (0 available); any Slc25a32 mutation (20 available)
Slc25a32em2Liliu mutation (0 available); any Slc25a32 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• decreased levels of specific acylcarnitines
• elevated levels of specific acylcarnitines

embryo
N
• mice born at normal Mendelian ratios

growth/size/body
N
• normal body weight and neonatal growth rate

behavior/neurological
N
• normal gait (no clubfoot)
• normal motor function in rotarod and forced swimming tests
• trend towards lower endurance in hanging wire test





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory