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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc25a32em1Liliu
endonuclease-mediated mutation 1, Li Liu
MGI:7520348
Summary 2 genotypes


Genotype
MGI:7520401
hm1
Allelic
Composition
Slc25a32em1Liliu/Slc25a32em1Liliu
Genetic
Background
C57BL/6-Slc25a32em1Liliu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a32em1Liliu mutation (0 available); any Slc25a32 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal gait (no clubfoot)
• normal motor function in hanging wire, rotarod and forced swimming tests

embryo
N
• mice born at normal Mendelian ratios

growth/size/body
N
• normal body weight and neonatal growth rate

homeostasis/metabolism
N
• normal folate intermediate levels in mitochondria
• normal carnitine levels




Genotype
MGI:7520405
ht2
Allelic
Composition
Slc25a32em1Liliu/Slc25a32em2Liliu
Genetic
Background
C57BL/6-Slc25a32em1Liliu/Slc25a32em2Liliu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a32em1Liliu mutation (0 available); any Slc25a32 mutation (20 available)
Slc25a32em2Liliu mutation (0 available); any Slc25a32 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• decreased levels of specific acylcarnitines
• elevated levels of specific acylcarnitines

embryo
N
• mice born at normal Mendelian ratios

growth/size/body
N
• normal body weight and neonatal growth rate

behavior/neurological
N
• normal gait (no clubfoot)
• normal motor function in rotarod and forced swimming tests
• trend towards lower endurance in hanging wire test





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory