About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Polr1aem2Knwea
endonuclease-mediated mutation 2, Kathryn Nicole Weaver
MGI:7526142
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Polr1aem2Knwea/Polr1aem2Knwea C57BL/6-Polr1aem2Knwea MGI:7526444
ht2
Polr1aem2Knwea/Polr1a+ C57BL/6-Polr1aem2Knwea MGI:7526440
ht3
Polr1aem2Knwea/Polr1atm1a(EUCOMM)Hmgu involves: C57BL/6 * C57BL/6N MGI:7526447
ht4
Polr1aem2Knwea/Polr1atm1d(EUCOMM)Hmgu involves: C57BL/6 * C57BL/6N MGI:7526448


Genotype
MGI:7526444
hm1
Allelic
Composition
Polr1aem2Knwea/Polr1aem2Knwea
Genetic
Background
C57BL/6-Polr1aem2Knwea
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem2Knwea mutation (0 available); any Polr1a mutation (94 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
N
• mice born at expected Mendelian ratios and sex ratios

growth/size/body
N
• no obvious phenotype




Genotype
MGI:7526440
ht2
Allelic
Composition
Polr1aem2Knwea/Polr1a+
Genetic
Background
C57BL/6-Polr1aem2Knwea
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem2Knwea mutation (0 available); any Polr1a mutation (94 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• mice born at expected Mendelian ratios and normal sex ratio

growth/size/body
• no obvious phenotype

reproductive system




Genotype
MGI:7526447
ht3
Allelic
Composition
Polr1aem2Knwea/Polr1atm1a(EUCOMM)Hmgu
Genetic
Background
involves: C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem2Knwea mutation (0 available); any Polr1a mutation (94 available)
Polr1atm1a(EUCOMM)Hmgu mutation (1 available); any Polr1a mutation (94 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
N
• mice born at expected Mendelian ratios and sex ratios

growth/size/body
N
• no obvious phenotype




Genotype
MGI:7526448
ht4
Allelic
Composition
Polr1aem2Knwea/Polr1atm1d(EUCOMM)Hmgu
Genetic
Background
involves: C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem2Knwea mutation (0 available); any Polr1a mutation (94 available)
Polr1atm1d(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (94 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• mice born at expected Mendelian ratios and sex ratios

growth/size/body
• no obvious phenotype





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory