About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Eif4e1bem2Dean
endonuclease-mediated mutation 2, Jurrien Dean
MGI:7539705
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Eif4e1bem2Dean/Eif4e1bem2Dean involves: C57BL/6 * DBA/2 MGI:7711749


Genotype
MGI:7711749
hm1
Allelic
Composition		 Eif4e1bem2Dean/Eif4e1bem2Dean
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif4e1bem2Dean mutation (1 available); any Eif4e1b mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system

cellular
maternal effect ( J:337681 )
• although eggs from homozygous females are able to be fertilized by wild-type males, none progress beyond the two-cell stage when cultured in vitro and the two-cell arrest occurs in vivo




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory