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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Eif4e1bem2Dean
endonuclease-mediated mutation 2, Jurrien Dean
MGI:7539705
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Eif4e1bem2Dean/Eif4e1bem2Dean involves: C57BL/6 * DBA/2 MGI:7711749


Genotype
MGI:7711749
hm1
Allelic
Composition		 Eif4e1bem2Dean/Eif4e1bem2Dean
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif4e1bem2Dean mutation (1 available); any Eif4e1b mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system

cellular
maternal effect ( J:337681 )
• although eggs from homozygous females are able to be fertilized by wild-type males, none progress beyond the two-cell stage when cultured in vitro and the two-cell arrest occurs in vivo




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory