Phenotypes associated with this allele

• Allele Symbol: Tg(Pgc-cre,-secNluc)#Hcz
• Allele Name: transgene insertion, Hua-Chuan Zheng
• Allele ID: MGI:7543061
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pten^tm1Hwu/Pten^tm1Hwu Tg(Pgc-cre,-secNluc)#Hcz/0	involves: 129S4/SvJae	MGI:7543156

Genotype
MGI:7543156

cn1

• Allelic Composition: Pten^tm1Hwu/Pten^tm1Hwu; Tg(Pgc-cre,-secNluc)#Hcz/0
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary adenocarcinoma incidence ( J:338079 )

♀ • in mice with two or more pregnancies

♀ • however, virgin conditional mice do not develop breast cancer even after exposure to estrogen or progesterone and mice that do not breastfeed after more than 2 births fail to develop breast cancer

integument

increased mammary adenocarcinoma incidence ( J:338079 )

♀ • in mice with two or more pregnancies

♀ • however, virgin conditional mice do not develop breast cancer even after exposure to estrogen or progesterone and mice that do not breastfeed after more than 2 births fail to develop breast cancer

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:338079 )

♀ • in mice with two or more pregnancies

♀ • however, virgin conditional mice do not develop breast cancer even after exposure to estrogen or progesterone and mice that do not breastfeed after more than 2 births fail to develop breast cancer