Phenotypes associated with this allele

• Allele Symbol: Gm26330^em1Liuq
• Allele Name: endonuclease-mediated mutation 1, Liuqing Yang
• Allele ID: MGI:7543240
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gm26330^em1Liuq/Gm26330^em1Liuq	C57BL/6-Gm26330^em1Liuq	MGI:7543286

Genotype
MGI:7543286

hm1

• Allelic Composition: Gm26330^em1Liuq/Gm26330^em1Liuq
• Genetic Background: C57BL/6-Gm26330^em1Liuq

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:341056 )

increased percent body fat/body weight ( J:341056 )

behavior/neurological

behavior/neurological phenotype ( J:341056 )

N • normal water intake in females

N • normal food intake in males

increased fluid intake ( J:341056 )

♂ • increased water intake in males

♂ • normal water intake in females

increased food intake ( J:341056 )

♀ • normal food intake in males

♀ • increased food intake in females

endocrine/exocrine glands

enlarged pancreatic islets ( J:341056 )

growth/size/body

obese ( J:341056 )

hematopoietic system

decreased NK cell number ( J:341056 )

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:341056 )

N • normal serum leptin and ghrelin levels

increased circulating insulin level ( J:341056 )

increased circulating triglyceride level ( J:341056 )

increased circulating alanine transaminase level ( J:341056 )

increased circulating aspartate transaminase level ( J:341056 )

decreased body temperature ( J:341056 )

decreased carbon dioxide production ( J:341056 )

decreased oxygen consumption ( J:341056 )

impaired glucose tolerance ( J:341056 )

immune system

decreased NK cell number ( J:341056 )

liver/biliary system

hepatic steatosis ( J:341056 )

renal/urinary system

polyuria ( J:341056 )