All Phenotypes Trmt6<em1Hbgl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Trmt6^em1Hbgl
endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI:7543517

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tg(Cd4-cre)1Cwi/0 Trmt6^em1Hbgl/Trmt6^em1Hbgl	involves: C57BL/6 * DBA/2J	MGI:7543561

Allelic Composition	Tg(Cd4-cre)1Cwi/0 Trmt6^em1Hbgl/Trmt6^em1Hbgl
Genetic Background	involves: C57BL/6 * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Cd4-cre)1Cwi mutation (10 available)
Trmt6^em1Hbgl mutation (0 available); any Trmt6 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased T cell proliferation ( J:336736 )

• after treatment with anti-CD3and anti-CD28 antibodies

decreased CD4-positive, alpha-beta T cell number ( J:336736 )

• decreased in the spleen

hematopoietic system

decreased T cell proliferation ( J:336736 )

• after treatment with anti-CD3and anti-CD28 antibodies

decreased CD4-positive, alpha-beta T cell number ( J:336736 )

• decreased in the spleen

cellular

decreased T cell proliferation ( J:336736 )

• after treatment with anti-CD3and anti-CD28 antibodies

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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