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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Degs2tm1Akih
targeted mutation 1, Akio Kihara
MGI:7543601
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Degs2tm1Akih/Degs2tm1Akih Not Specified MGI:7543602


Genotype
MGI:7543602
hm1
Allelic
Composition		 Degs2tm1Akih/Degs2tm1Akih
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Degs2tm1Akih mutation (0 available); any Degs2 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased ceramide level ( J:335270 )
• reduced ceramides containing phytosphingosine (PHS-CER) in the skin
• more abundant very-long-fatty acid PHS-CER than long-chain ones

integument
integument phenotype ( J:335270 )
N
• mice exhibit normal skin barrier function




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory