About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Degs2tm1Akih
targeted mutation 1, Akio Kihara
MGI:7543601
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Degs2tm1Akih/Degs2tm1Akih Not Specified MGI:7543602


Genotype
MGI:7543602
hm1
Allelic
Composition		 Degs2tm1Akih/Degs2tm1Akih
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Degs2tm1Akih mutation (0 available); any Degs2 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased ceramide level ( J:335270 )
• reduced ceramides containing phytosphingosine (PHS-CER) in the skin
• more abundant very-long-fatty acid PHS-CER than long-chain ones

integument
integument phenotype ( J:335270 )
N
• mice exhibit normal skin barrier function




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory