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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Asxl3em1Jlp
endonuclease-mediated mutation 1, Jose de la Pompa
MGI:7543632
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Apcdd1em1Jlp/Apcdd1+
Asxl3em1Jlp/Asxl3+
Mib1em1Jlp/Mib1+ 		C57BL/6-Apcdd1em1Jlp Asxl3em1Jlp Mib1em1Jlp MGI:7544919


Genotype
MGI:7544919
cx1
Allelic
Composition		 Apcdd1em1Jlp/Apcdd1+
Asxl3em1Jlp/Asxl3+
Mib1em1Jlp/Mib1+
Genetic
Background		 C57BL/6-Apcdd1em1Jlp Asxl3em1Jlp Mib1em1Jlp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apcdd1em1Jlp mutation (0 available); any Apcdd1 mutation (50 available)
Asxl3em1Jlp mutation (0 available); any Asxl3 mutation (99 available)
Mib1em1Jlp mutation (0 available); any Mib1 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
thin ventricle myocardium compact layer ( J:338889 )
• in E16.5 embryos
• reduced compact-to-trabecular myocardium ratio in E16.5 embryos
dilated heart ( J:338889 )
• dilated atria and ventricles in adults
increased cardiac output ( J:338889 )
• elevated systolic and end diastolic volume in adults

muscle
thin ventricle myocardium compact layer ( J:338889 )
• in E16.5 embryos
• reduced compact-to-trabecular myocardium ratio in E16.5 embryos




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory