About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apcdd1em1Jlp
endonuclease-mediated mutation 1, Jose de la Pompa
MGI:7543634
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Apcdd1em1Jlp/Apcdd1+
Asxl3em1Jlp/Asxl3+
Mib1em1Jlp/Mib1+ 		C57BL/6-Apcdd1em1Jlp Asxl3em1Jlp Mib1em1Jlp MGI:7544919


Genotype
MGI:7544919
cx1
Allelic
Composition		 Apcdd1em1Jlp/Apcdd1+
Asxl3em1Jlp/Asxl3+
Mib1em1Jlp/Mib1+
Genetic
Background		 C57BL/6-Apcdd1em1Jlp Asxl3em1Jlp Mib1em1Jlp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apcdd1em1Jlp mutation (0 available); any Apcdd1 mutation (50 available)
Asxl3em1Jlp mutation (0 available); any Asxl3 mutation (99 available)
Mib1em1Jlp mutation (0 available); any Mib1 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
thin ventricle myocardium compact layer ( J:338889 )
• in E16.5 embryos
• reduced compact-to-trabecular myocardium ratio in E16.5 embryos
dilated heart ( J:338889 )
• dilated atria and ventricles in adults
increased cardiac output ( J:338889 )
• elevated systolic and end diastolic volume in adults

muscle
thin ventricle myocardium compact layer ( J:338889 )
• in E16.5 embryos
• reduced compact-to-trabecular myocardium ratio in E16.5 embryos




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory