About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Wdfy4em1Jkln
endonuclease-mediated mutation 1, Justin Kline
MGI:7545162
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Wdfy4em1Jkln/Wdfy4em1Jkln C57BL/6J-Wdfy4em1Jkln MGI:7545236


Genotype
MGI:7545236
hm1
Allelic
Composition
Wdfy4em1Jkln/Wdfy4em1Jkln
Genetic
Background
C57BL/6J-Wdfy4em1Jkln
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wdfy4em1Jkln mutation (0 available); any Wdfy4 mutation (142 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal numbers of T cells in secondary lymphoid organs
• reduced CD103+ CD11bneg migratory cDC1 cells in the mesenteric lymph nodes

neoplasm
• mice fail to reject 1969 sarcoma cells unlike wild-type mice

hematopoietic system
• reduced CD103+ CD11bneg migratory cDC1 cells in the mesenteric lymph nodes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory