All Phenotypes Bdnf<tm1.1Tmiz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Bdnf^tm1.1Tmiz
targeted mutation 1.1, Toshiyuki Mizui
MGI:7545595

Summary

2 genotypes

Allelic Composition	Bdnf^tm1.1Tmiz/Bdnf^tm1.1Tmiz
Genetic Background	B6.Cg-Bdnf^tm1.1Tmiz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bdnf^tm1.1Tmiz mutation (0 available); any Bdnf mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:303078 )

N	• no heart malformations or intramyocardial hemorrhage at age 7 days • normal cardiac endothelial cell morphology

growth/size/body

growth/size/body region phenotype ( J:303078 )

N	• normal body weight

Allelic Composition	Bdnf^tm1.1Tmiz/Bdnf⁺
Genetic Background	B6.Cg-Bdnf^tm1.1Tmiz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bdnf^tm1.1Tmiz mutation (0 available); any Bdnf mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased food intake ( J:303078 )

• after social isolation between age 6 and 14 weeks

behavioral despair ( J:303078 )

• increased immobility in tail suspension test after social isolation between age 6 and 14 weeks

abnormal nest building behavior ( J:303078 )

• after social isolation between age 6 and 14 weeks

growth/size/body

increased body weight ( J:303078 )

• after social isolation between age 6 and 14 weeks

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