mortality/aging
• no mice are present at E7.5 or E13.5
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Allele Symbol Allele Name Allele ID |
Fignl1tm1.1Osb targeted mutation 1.1, Research Institute for Microbial Diseases, Osaka University MGI:7546940 |
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Summary |
4 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• no mice are present at E7.5 or E13.5
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• cells are fully lost before pachynema
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• cells are fully lost before pachynema
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• 6-fold lower than in control mice with reduced numbers of late spermatocytes and spermatids
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• abnormal meiotic recombination with cells fully lost before pachynema
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• 6-fold lower than in control mice with reduced numbers of late spermatocytes and spermatids
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• abnormal meiotic recombination with cells fully lost before pachynema
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• however, RAD51/DMC1 assembly defects observed in Swsap1tm1.1Osb homozygotes is rescued
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• however, RAD51/DMC1 assembly defects observed in Swsap1tm1.1Osb homozygotes is rescued
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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