All Phenotypes Smg6<tm1.1Tac> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Smg6^tm1.1Tac
targeted mutation 1.1, Taconic
MGI:7571582

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Per2^tm1Jt/Per2⁺ Smg6^tm1.1Tac/Smg6^tm1.1Tac	involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J	MGI:7571625

Allelic Composition	Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Per2^tm1Jt/Per2⁺ Smg6^tm1.1Tac/Smg6^tm1.1Tac
Genetic Background	involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Alb^{tm1(cre/ERT2)Mtz} mutation (2 available); any Alb mutation (97 available)
Per2^tm1Jt mutation (2 available); any Per2 mutation (73 available)
Smg6^tm1.1Tac mutation (0 available); any Smg6 mutation (99 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal locomotor circadian rhythm ( J:342742 )

• when entrained on a light phase feeding regimen

prolonged circadian behavior period ( J:342742 )

• 3-hours longer period in liver explants

abnormal circadian behavior phase ( J:342742 )

• phase differences at the pre-mRNA level for many core clock genes in liver

abnormal circardian behavior entrainment ( J:342742 )

• when entrained on a light phase feeding regimen

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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