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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itpripl1em1Smoc
endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI:7577021
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itpripl1em1Smoc/Itpripl1em1Smoc C57BL/6J-Itpripl1em1Smoc MGI:7639945


Genotype
MGI:7639945
hm1
Allelic
Composition		 Itpripl1em1Smoc/Itpripl1em1Smoc
Genetic
Background		 C57BL/6J-Itpripl1em1Smoc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpripl1em1Smoc mutation (0 available); any Itpripl1 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal testis morphology ( J:348064 )
• mice show an increase in T cell infiltration within the testis and testis shows condensed cell infiltrates and moderate shrinkage in certain tissue regions
• however, no histological abnormalities are seen in the heart, liver, spleen, brain, salivary gland, or pancreas

endocrine/exocrine glands
abnormal testis morphology ( J:348064 )
• mice show an increase in T cell infiltration within the testis and testis shows condensed cell infiltrates and moderate shrinkage in certain tissue regions
• however, no histological abnormalities are seen in the heart, liver, spleen, brain, salivary gland, or pancreas

cellular




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory