Analysis Tools|
Allele Symbol Allele Name Allele ID |
Alkal1tm1Schl targeted mutation 1, Joseph Schlessinger MGI:7578839 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• double knockout mice fed a standard chow diet show a significantly lower body weight than double heterozygous controls at 26 weeks of age
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• double knockout mice fed a standard chow diet gain significantly less weight than double heterozygous controls
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice fed a standard chow diet show a significantly lower body weight than double heterozygous controls at 26 weeks of age
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• mice fed a standard chow diet gain significantly less weight than double heterozygous controls, with body weight kinetics similar to those in seen in double knockout mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice fed a standard chow diet show no differences in body weight kinetics relative to double heterozygous controls, indicating that Alkal2 deficiency causes thinness whereas Alkal1 deficiency does not
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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