Phenotypes associated with this allele

• Allele Symbol: Dync2i2^{Tn(pb-Act-RFP)1.1Zhu}
• Allele Name: transposon insertion 1.1, Yuan Zhuang
• Allele ID: MGI:7580877
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dync2i2^Tn(pb-Act-RFP)1.1Zhu/Dync2i2^Tn(pb-Act-RFP)1.1Zhu	involves: C57BL/6 * FVB/NJ	MGI:7608410

Genotype
MGI:7608410

hm1

• Allelic Composition: Dync2i2^{Tn(pb-Act-RFP)1.1Zhu}/Dync2i2^{Tn(pb-Act-RFP)1.1Zhu}
• Genetic Background: involves: C57BL/6 * FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:335806 )

• die between E10.5 and E11.5

nervous system

open neural tube ( J:335806 )

• open heads in some embryos at E10.5

• more embryos have an open caudal neural tube at E10.5

decreased midbrain size ( J:335806 )

• at E10.5

abnormal telencephalon morphology ( J:335806 )

• smaller telencephalic evagination at E10.5

embryo

embryonic growth retardation ( J:335806 )

• severe developmental retardation and malformation at E1.5

open neural tube ( J:335806 )

• open heads in some embryos at E10.5

• more embryos have an open caudal neural tube at E10.5

cellular

abnormal cilium morphology ( J:335806 )

• decrease in expression of acetyl-Tubulin, a marker for cilia, in the neural tube

cardiovascular system

abnormal heart looping ( J:335806 )

• expanded heart loop at E10.5

growth/size/body

embryonic growth retardation ( J:335806 )

• severe developmental retardation and malformation at E1.5