Phenotypes associated with this allele

• Allele Symbol: Tspan15^em1Psf
• Allele Name: endonuclease-mediated mutation 1, Paul Saftig
• Allele ID: MGI:7594194
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tspan15^em1Psf/Tspan15^em1Psf	C57BL/6N-Tspan15^em1Psf	MGI:7595653

Genotype
MGI:7595653

hm1

• Allelic Composition: Tspan15^em1Psf/Tspan15^em1Psf
• Genetic Background: C57BL/6N-Tspan15^em1Psf

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:345187 )

• a slight increase in mortality rate of 16% within the first 3 weeks of birth, but surviving mice show normal lifespan

nervous system

nervous system phenotype ( J:345187 )

N • mice do not show any obvious synaptic changes of hippocampal CA1 neurons, with normal dendritic spines and hippocampal morphology

N • no overt neurological symptoms are seen in aged mice