Phenotypes associated with this allele

• Allele Symbol: Sspo^em1Lehm
• Allele Name: endonuclease-mediated mutation 1, Maria K Lehtinen
• Allele ID: MGI:7595634
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sspo^em1Lehm/Sspo^em1Lehm	involves: C57BL/6	MGI:7595637

Genotype
MGI:7595637

hm1

• Allelic Composition: Sspo^em1Lehm/Sspo^em1Lehm
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal Reissner's fiber morphology ( J:344687 )

• absence of Reissner's fiber material

small lateral ventricles ( J:344687 )

• on average a ~35% reduction in volume

• however, overall brain size is similar to controls

small third ventricle ( J:344687 )

• on average a ~35% reduction in volume

• however, overall brain size is similar to controls

skeleton

abnormal vertebral column morphology ( J:344687 )

• minor defects in spinal curvature that tend to build up with age but do not exceed 7.3 degrees

behavior/neurological

behavior/neurological phenotype ( J:344687 )

N • basic motor function and mobility are similar to controls