About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ces1ce
variant e
MGI:7595768
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
a/a
Ces1ce/Ces1ce
B6;D2-a Ces1ce/EiJ MGI:7596325


Genotype
MGI:7596325
cx1
Allelic
Composition
a/a
Ces1ce/Ces1ce
Genetic
Background
B6;D2-a Ces1ce/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Ces1ce mutation (2 available); any Ces1c mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 3-fold decreased in total plasma esterases activity compared with B6D2F1
• 200-fold reduction in SN-38 production after incubation with CPT-11 in vitro





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory