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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Eogttm1.1Okaj
targeted mutation 1.1, Tetsuya Okajima
MGI:7607995
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Eogttm1.1Okaj/Eogttm1.1Okaj
Tg(Tek-cre)1Ywa/0 		involves: C57BL/6 * C57BL/6J * SJL MGI:7640065


Genotype
MGI:7640065
cn1
Allelic
Composition		 Eogttm1.1Okaj/Eogttm1.1Okaj
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eogttm1.1Okaj mutation (0 available); any Eogt mutation (44 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal retina vasculature morphology ( J:254752 )
• vessel branching is increased in P5 and P15 retinas
• however, length of alphaSMA+ vessels and vessel progression in P5 retinas is not altered
increased vascular permeability ( J:254752 )
• retinas show aberrant fibrinogen staining and sulfo-NHS-LC-biotin extravasation indicating reduced vessel integrity

vision/eye
abnormal retina vasculature morphology ( J:254752 )
• vessel branching is increased in P5 and P15 retinas
• however, length of alphaSMA+ vessels and vessel progression in P5 retinas is not altered




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory