Phenotypes associated with this allele

• Allele Symbol: Crlf3^em1Gtm
• Allele Name: endonuclease-mediated mutation 1, David H Gutmann
• Allele ID: MGI:7608098
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Crlf3^em1Gtm/Crlf3^+	C57BL/6J-Crlf3^em1Gtm	MGI:7608104

Genotype
MGI:7608104

ht1

• Allelic Composition: Crlf3^em1Gtm/Crlf3⁺
• Genetic Background: C57BL/6J-Crlf3^em1Gtm

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:344359 )

N • normal axon length in cultured hippocampal neurons

N • normal hippocampus cellular composition

abnormal dendrite morphology ( J:344359 )

• 39% shorter dendrites in cultured hippocampal neurons

• normal number of dendrites in cultured hippocampal neurons

abnormal dendrite arborization pattern ( J:344359 )

• 48% fewer branchpoints per dendrite in cultured hippocampal neurons

behavior/neurological

behavior/neurological phenotype ( J:344359 )

N • normal social/emotional and physical behavior